Bexitrol F 25/250 HFA Inhaler | Asthma | 120 metered spray | ePharma
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Bexitrol F 25/250 HFA Inhaler

Generic: Salmeterol + Fluticasone Propionate

Type: Inhalation

Pack Size: 1 Pc

Salmeterol and Fluticasone Propionate are both ingredients in the Bexitrol F 25/250 HFA Inhaler. It is used to treat chronic obstructive pulmonary disease (COPD), a lung disorder in which the airflow is obstructed and causes breathing difficulties, as well as asthma, a condition that involves constriction of the airways. The muscles in your airways are relaxed and widened as a result of it. 


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✅ Description:

  • Bexitrol F 25/250 HFA Inhaler is a combination medication containing (Salmeterol 25mcg + Fluticasone Propionate 250mcg). Fluticasone belongs to the corticosteroid group of medicines, while Salmeterol is a bronchodilator. This inhaler is primarily used for the treatment of asthma and chronic obstructive pulmonary disease (COPD), helping to reduce symptoms and prevent flare-ups.
  • Asthma is a chronic respiratory condition characterized by airway inflammation, swelling, and narrowing, which results in symptoms such as wheezing, difficulty breathing, chest pain, and coughing. COPD is a lung disease that causes chronic inflammation and obstructed airflow in the airways, leading to symptoms like wheezing, breathing difficulties, coughing with mucus production, and chest pain.
  • When using the Bexitrol F 25/250 HFA Inhaler, it is important to follow your doctor's instructions and use it regularly as prescribed. It should only be used for inhalation, so avoid swallowing the medicine. Do not discontinue its use without consulting your doctor, even if your symptoms improve. The inhaler is suitable for both adults and adolescents aged 12 years and above.
  • It is crucial to note that the Bexitrol F 25/250 HFA Inhaler should not be used to relieve sudden asthma attacks. In such situations, it is recommended to seek medical assistance or use a fast-acting "rescue" inhaler containing salbutamol to alleviate the symptoms.
  • Before using the Bexitrol F 25/250 HFA Inhaler, inform your doctor if you have any lung infections, liver problems, or heart problems. Additionally, disclose any other medical conditions you may have, such as diabetes, hypertension, seizures, overactive thyroid function, osteoporosis, adrenal gland issues, or a weakened immune system, as a precautionary measure.
  • For pregnant and breastfeeding women, the use of Bexitrol F 25/250 HFA Inhaler should only be considered if deemed necessary by the physician.
  • Common side effects of using Bexitrol F 25/250 HFA Inhaler include headaches, cold symptoms, oral thrush or oral sores, throat irritation, hoarseness, muscle pain, and joint pain. If any of these side effects worsen or persist, contact your doctor.

Safety Advices


Alcohol
CAUTION

The interaction of Bexitrol F 25/250 HFA Inhaler with alcohol is unknown. However, as a precautionary measure, it is advisable not to take or limit alcohol.


Pregnancy
CONSULT YOUR DOCTOR

The safety of Bexitrol F 25/250 HFA Inhaler in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.


Breastfeeding
CONSULT YOUR DOCTOR

It is unknown whether Bexitrol F 25/250 HFA Inhaleris excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.


Driving

Do not drive or operate any heavy tools or machines if your ability is affected by Bexitrol F 25/250 HFA Inhaler.


Kidney
CONSULT YOUR DOCTOR

If you have any concerns regarding using Bexitrol F 25/250 HFA Inhaler in patients with kidney problems, your doctor may adjust the dose as required. Please consult your doctor.


Liver
CAUTION

Bexitrol F 25/250 HFA Inhaler should be taken with caution in patients with liver diseases. Therefore, consult your doctor before using it.

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✔️ Uses of Bexitrol F 25/250 HFA Inhaler
  • Asthma
  • Chronic obstructive pulmonary disease (COPD)
✔️ How does Bexitrol F 25/250 HFA Inhaler work?

Bexitrol F 25/250 HFA is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator that works by relaxing the muscles in the airways and widening the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

✔️ Side Effects ofBexitrol F 25/250 HFA Inhaler
  • Nausea
  • Vomiting
  • Respiratory tract infection
  • Fungal infection of the mouth
  • Sore throat
  • Headache
  • Hoarseness of voice
  • Cough
  • Musculoskeletal (bone, muscle, or joint) pain
  • Increased heart rate
✔️ Quick Suggestions:
  • This medication is intended for inhalation use only and should not be swallowed.
  • Take the inhaler at the same time each day for consistent effectiveness.
  • It is not a fast-acting medication and should not be used for immediate relief of sudden breathing difficulties. For such situations, use a rescue inhaler as prescribed.
  • A dry mouth may occur as a side effect. To alleviate this, rinse your mouth frequently, maintain good oral hygiene, increase water intake, and use sugarless candy.
  • After each inhalation, gargle with warm water to prevent fungal infections in the mouth and throat.
  • The first dose should be taken under medical supervision, as it may cause wheezing or bronchospasm immediately after use.
  • Your doctor may monitor your blood potassium levels regularly, as low oxygen levels and certain medications can lower potassium levels.
  • The absorption of Bexitrol F 25/250 HFA inhalers into the bloodstream is minimal, so serious side effects are unlikely. Maintaining a healthy diet and exercising regularly can strengthen your breathing muscles and boost your immune system.
  • Avoid certain foods that may worsen asthma symptoms, such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice.
  • Engaging in meditation, deep breathing exercises, regular physical activity, and progressive muscle relaxation techniques can help reduce stress and the risk of an asthma attack.
  • Quitting smoking is recommended as it can improve the effectiveness of the inhaler and prevent further irritation of the lungs.
  • Learning proper breathing exercises will help you maximize air movement in and out of your lungs.
  • Carry a prescribed inhaler for use during sudden asthma attacks.
✔️ Indication of Bexitrol F 25/250 HFA inhaler

Asthma

  • Asthma is a condition that causes the narrowing of the airways with excessive mucous production, leading to breathing difficulty. Airtec SF 125 Inhaler is used in the management of asthma.

Chronic obstructive pulmonary disease

  • Chronic obstructive pulmonary disease (COPD) refers to lung conditions that cause blockage of airflow, leading to breathing-related problems. Airtec SF 125 Inhaler is used in the treatment of COPD as it relaxes and widens the airways.
✔️ Pharmacology

Salmeterol is a long-acting beta 2-agonist that works locally in the lungs to promote bronchodilation. It helps to relax the smooth muscles in the airways, leading to improved airflow and relief of asthma symptoms. It is a long-acting medication, providing sustained bronchodilation for a specified duration.

Fluticasone, on the other hand, is a corticosteroid with predominantly glucocorticoid activity. It works by reducing inflammation in the airways, which is a key component of asthma. By decreasing airway inflammation, fluticasone helps to alleviate symptoms and prevent exacerbations or flare-ups of asthma.

When combined in Bexitrol F 25/250 HFA Inhalers, salmeterol, and fluticasone work synergistically to provide both bronchodilation and anti-inflammatory effects. This combination therapy is effective in managing asthma and chronic obstructive pulmonary disease (COPD) by addressing both the underlying inflammation and the bronchospasm associated with these conditions.

✔️ Dosage & Administration of Bexitrol F 25/250 HFA inhaler

Adult Dose

  • Inhalation Asthma Adult: A combination containing salmeterol 50 mcg and fluticasone propionate 100/250/500 mcg/dose of inhalation powder: 1 inhalation bid. A combination containing salmeterol 25 mcg and fluticasone propionate 50/125/250 mcg/dose of pressurized inhalation: 2 inhalation bid. Chronic obstructive pulmonary disease Adult: As combination containing salmeterol 50 mcg and fluticasone propionate 500 mcg/dose of inhalation powder: 1 inhalation bid.

Child Dose

  • Inhalation Asthma Child: 4-12 yr: As combination containing salmeterol 50 mcg and fluticasone propionate 100 mcg/ dose of inhalation powder: 1 inhalation bid; As combination containing salmeterol 25 mcg and fluticasone propionate 50 mcg/dose of pressurized inhalation: 2 inhalation bid. >12 yr: As combination containing salmeterol 50 mcg and fluticasone propionate 100/250/500 mcg/dose of inhalation powder: 1 inhalation bid; As combination containing salmeterol 50/125/250 mcg and fluticasone propionate 50 mcg/dose of pressurized inhalation: 2 inhalation bid.

Direction for use:

  • Take Bexitrol F 25/250 HFA Inhaler as prescribed by your doctor and use it every day until instructed otherwise.
  • It is important to use the inhaler for inhalation only and breathe the medicine into your lungs through your mouth, not your nose.
  • Refer to the enclosed leaflet for detailed instructions.
  • Before using the inhaler for the first time or after a period of non-use, prime the device by releasing two puffs into the air.
  • Place the mouthpiece in your mouth, ensuring a complete seal with your lips.
  • Breathe in slowly and deeply through your mouth while pressing the top of the canister firmly to release a puff of medicine.
  • Remove the inhaler from your mouth and hold your breath for about 10 seconds or as long as comfortable.
  • Wait approximately 30 seconds between each puff of medicine.
  • After each inhalation, wipe the mouthpiece with a dry tissue and close the device.
  • Rinse your mouth with water and spit it out or brush your teeth after inhalation.
  • The correct dose, duration, and number of puffs will be determined by your doctor based on your age, body weight, and the condition being treated.
  • Do not start using Bexitrol F 25/250 HFA Inhaler without proper instruction from your doctor or healthcare provider. If you find it difficult to use the device, your doctor may recommend a suitable spacer device.
  • Do not abruptly stop using the medicine or reduce the dose without consulting your doctor, as it may worsen your breathing symptoms.

It is always important to follow your doctor's instructions and seek their guidance if you have any concerns or difficulties with using the inhaler.

✔️ Interaction
  • Bexitrol F 25/250 HFA Inhaler may interact with various medications, including bronchodilators, steroids, heart-related medicines, drugs used to treat Hodgkin's disease, water pills, antibiotics, drugs used to lower high blood pressure, medicines to induce labor, antithyroid agents, antidepressants, antifungals, HIV medicines, and antiparkinson drugs.
  • It is important to inform your doctor if you are taking any of these medications before using Bexitrol F 25/250 HFA Inhaler.
  • Additionally, there is a potential interaction between Bexitrol F 25/250 HFA Inhalerand grapefruit or grapefruit juice. It is advisable to avoid consuming grapefruit or its juice while using this medication to prevent severe adverse effects.
  • If you have certain medical conditions such as high blood pressure, diabetes, chest or lung infection, hyperthyroidism, low potassium levels in the blood, glaucoma, cataracts, osteoporosis, tuberculosis, or heart, liver, or adrenal gland problems, it is important to inform your doctor before using Bexitrol F 25/250 HFA Inhaler.
✔️ Contraindications

This is contraindicated in patients with a history of hypersensitivity to any of the ingredients.

✔️ Pregnancy & Lactation

Drugs should only be administered during pregnancy and lactation if the predicted benefit to the mother outweighs any potential danger to the fetus or child. Salmeterol Xinafoate and Fluticasone Propionate have insufficient expertise in human pregnancy and lactation. There is no information about human breast milk.

✔️ Precautions & Warnings
  • Pulmonary TB, severe cardiovascular disorders, heart rhythm abnormalities, DM, thyrotoxicosis, hypokalaemia. Patients at risk of decreased bone mineral content (e.g. smoking, old age, sedentary lifestyle, poor nutrition, family history of osteoporosis, or long-term use of drugs that may decrease bone mass (e.g. anticonvulsants and corticosteroids). Do not stop therapy abruptly; therapy should be down-titrated. Advise patient to rinse mouth after inhalation. Monitor the height of children on prolonged therapy. Pregnancy, lactation.
  • This medicine is for inhalation only. The tablet should not be swallowed.
  • It should be taken at the same time each day.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
  • A dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake, and sugarless candy may help.
  • Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
  • Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after use.
  • Your doctor may regularly monitor your blood potassium level as the low oxygen level in the blood (hypoxia) and medicines such as Bexitrol F 25/250 HFA can lower blood potassium level.
  • Only minuscule amounts of Bexitrol F 25/250 HFA may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
✔️ Storage Conditions

Pressurized canisters, do not puncture, break or incinerate even when apparently empty. Avoid storage in direct sunlight or heat. Store below 30°C. Keep away from eyes. Keep away from children.

Frequently Asked Questions (FAQ)

Bexitrol F 25/250 HFA Inhaler is used to treat asthma and chronic obstructive pulmonary disease (COPD). It also helps in reducing flare-ups of COPD symptoms.

Bexitrol F 25/250 HFA Inhaler is considered safe at doses prescribed by the physician.

Bexitrol F 25/250 HFA Inhaler is considered safe for use in children and adolescents aged 12 years or above. However, it is not recommended for use in children younger than 12 years due to lack of safety data. Kindly consult your doctor before taking.

Yes. Bexitrol F 25/250 HFA Inhaler may cause fungal infections of the mouth (oral thrush). To avoid this, make sure to rinse your mouth with water after inhaling the medicine. However, if an infection develops, consult your doctor.

Some individuals taking Bexitrol F 25/250 HFA Inhaler may experience an increase in heart rate. If this occurs, one should contact his/her doctor immediately.
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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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